Bob Dole -
My mother-in-law lives just south of the 60 over by the airport. I only mean that to head west into LA you have to take one of the three afformentioned expressways. To get to the 210, I drive the 60 for about ten minutes to either 71 North to 210 West or follow 60 West to 57/210 North which transistions into 210 West. I wouldn't take the 60 to SFMM.
Chitown -
In the interest of not confusing you (and depending where you are in Ontario), take one of the side streets (Central, Mountain, etc.) to the 10 West. Take 10 West about 10 miles - you'll have options at this point for the 10 West, 57 South or 210 North (I think it's North but it may be labeled west). Whatever it is - get on the 210 North. (Side note: if you take 57 South for about 25 miles you'll end up in Anaheim and start seeing signs for Disneyland). You'll actually head north for about 4 miles before you actually start going West. Take the 210 West - you'll pass Glendora, Durate, Monrovia, Pasadena...keep going till you hit I-5 (you can't miss it - 210 dead ends into the 5). Take 5 North and exit on Magic Mountain Ave or Pkwy (whatever it is). Make a left at the bottom and follow the signs. Your drive distance will be a bit longer but it's really the best way.
For grins (if you're so inclined)you CAN take the 10 to 5 North - but you'll hit more traffic and smog. :)
Where in Chicago do you live? My younger brother lives just north of downtown and works in Highland Park (very nice area). My wife and I went to his graduation (from Loyola) and came across the Skyway and went through downtown where it curves (94 North maybe?) on our way to Elgin(?) Anyhow, what a beautiful city - great place to party as well, and the restaurants kick butt as well. Ever eat at Winston's?